SGD: Enery Metabolism in Muscle - Inhibitors and mutations of ETC proteins

Musculoskeletal Block, MD Phase I 2011/2012
Prepared by Dr Aini Suzana Adenan
17 October 2011

SGD
7. Inhibitors of the electron transport chain proteins and mutations in the mitochondrial and nuclear DNA that encodes them can cause reduced activity of the electron transport chain. Explain why impairment of the electron transport chain can cause lactic acidosis.