Thursday 10 November 2011

First Cousin Marriages

Why are first cousin marriages not favoured?
What are the dangers of first cousin marriages?
Is it true that first cousin marriages result in higher chances of getting any genetic disease?
Is it true that first cousin marriages result in higher chances of getting heart disease?
Do first cousin marriages lend themselves to pediatric or adult heart disease?
Are first cousin marriages healthy or not?
How can we study first cousin marriages properly and see that they link/do not link to genetic diseases, especially heart disease, specifically congenital heart disease in babies/pediatrics and ischaemic heart disease in adults?

Sources:
Ann Pediatr Cardiol. 2011 Jul;4(2):111-6.
Assessing the influence of consanguinity on congenital heart disease.
Centre for Comparative Genomics, Murdoch University, and School of Medical Sciences, Edith Cowan University, Perth, Australia.

Community Genet. 2007;10(1):27-31.
Influence of consanguinity on the pattern of familial aggregation of congenital cardiovascular anomalies in an outpatient population: studies from the eastern province of Saudi Arabia.
Division of Pediatric Cardiology, Dhahran Health Center, Dhahran, Saudi Arabia. Seliem@email.chop.edu

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