Friday 8 April 2011

Origin of WHHL rabbits

Professor Yoshio Watanabe
Dr Yoshio Watanabe (1926-2008) was 82 when he died. He was a former professor at the Institute for Experimental Animals, School of Medicine, Kobe University, Japan. He discovered a male Japanese white rabbit in 1973 that showed hyperlipidemia despite feeding on a normal standard diet (Exp Anim 1977; 26: 35-42 (Japanese); Bull Azabu Vet Coll 1977; 2: 99-124 (Japanese); Atherosclerosis 1980; 36: 261-268). He confirmed the hyperlipidemia of this rabbit was inherited recessively from its parents.

WHHL rabbit
Dr Watanabe established this rabbit mutant strain in 1980 and named it WHHL (Watanabe heritable hyperlipidemic) rabbit ( Atherosclerosis 1980; 36: 261-268). After establishment of this WHHL rabbit strain, Dr Watanabe began to distribute the WHHL rabbits to many researchers worldwide.

Source: http://www.med.kobe-u.ac.jp/iea/wol.html

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