There are 2 types of hyperlipidaemias, one is genetic and the other is acquired. In genetic hyperlipidaemias, one or more defective gene(s) is/are involved, either in the enzymes of synthesis of the lipoproteins or in the metabolism of lipoproteins. When one gene is involved, it is termed monogenic hyperlipidaemia. When more than one gene is involved, it is termed polygenic hyperlipidaemia. Which is worse or more severe? It depends.
In Perth, Prof. Frank van Bockxmeer has set up his lab to look at genetic hyperlipidaemias. He is no stranger to lipid research and hyperlipidaemia research or genetics research involving hyperlipidaemias. Please take a look at some of his 65 publications to date here:
https://www.researchgate.net/search.Search.html?offset=0&query=frank+van+bockxmeer
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